Thursday 10 May 2012

Hyosyne Drops


Pronunciation: HYE-oh-SYE-a-meen
Generic Name: Hyoscyamine
Brand Name: Examples include Hyosyne and Colidrops


Hyosyne Drops are used for:

Treating certain stomach, intestinal, and bladder conditions, including spasms. It is used to control stomach secretions and cramps. It is used to relieve the symptoms of colic, runny nose, and Parkinson-like problems. It is used to treat excessive sweating or saliva production. It may also be used for other conditions as determined by your doctor.


Hyosyne Drops are an anticholinergic agent. It works by decreasing the motion of muscles in the stomach, intestines, and bladder. It also decreases the production of stomach acid.


Do NOT use Hyosyne Drops if:


  • you are allergic to any ingredient in Hyosyne Drops

  • you have severe esophagus problems (eg, irritation, narrowing); a blockage of the stomach, bowel, or bladder; bowel motility problems; or severe bowel problems (eg, severe ulcerative colitis, toxic megacolon)

  • you have glaucoma, myasthenia gravis, or heart problems caused by severe bleeding

Contact your doctor or health care provider right away if any of these apply to you.



Before using Hyosyne Drops:


Some medical conditions may interact with Hyosyne Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have nerve problems, prostate problems, esophagus problems (eg, reflux), stomach or bowel problems, heart or blood vessel problems (eg, fast or irregular heartbeat, heart failure, coronary heart disease), hiatal hernia, kidney problems, an overactive thyroid, high blood pressure, urinary problems, paralysis, or brain damage, or if you are at risk for glaucoma

  • if you have diarrhea or fever, have been very ill, or are in poor health

Some MEDICINES MAY INTERACT with Hyosyne Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Amantadine, antihistamines (eg, diphenhydramine), haloperidol, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), other anticholinergics (eg, scopolamine), phenothiazines (eg, thioridazine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Hyosyne Drops's side effects

  • Narcotic pain medicines (eg, codeine) or potassium chloride because the risk of their side effects may be increased by Hyosyne Drops

  • Ketoconazole or metoclopramide because their effectiveness may be decreased by Hyosyne Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hyosyne Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Hyosyne Drops:


Use Hyosyne Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Hyosyne Drops are usually taken 30 to 60 minutes before a meal. Follow your doctor's instructions for taking Hyosyne Drops.

  • Use the dropper that comes with Hyosyne Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you also take antacids, take Hyosyne Drops before meals and the antacid after meals, unless directed otherwise by your doctor.

  • If you miss a dose of Hyosyne Drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Hyosyne Drops.



Important safety information:


  • Hyosyne Drops may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Hyosyne Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Hyosyne Drops; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

  • Do not become overheated or dehydrated in hot weather or while you are being active; heatstroke may occur.

  • Drink plenty of fluids, maintain good oral hygiene, and suck on sugarless hard candy to relieve dry mouth.

  • Proper dental care is important while you are taking Hyosyne Drops. Brush and floss your teeth and visit the dentist regularly.

  • Hyosyne Drops may make your eyes more sensitive to sunlight. It may help to wear sunglasses.

  • Tell your doctor or dentist that you take Hyosyne Drops before you receive any medical or dental care, emergency care, or surgery.

  • Use Hyosyne Drops with caution in the ELDERLY; they may be more sensitive to its effects, especially constipation, trouble urinating, dry mouth, drowsiness, agitation, confusion, excitability, or memory problems.

  • Caution is advised when using Hyosyne Drops in CHILDREN; they may be more sensitive to its effects, including excitability.

  • Hyosyne Drops should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.

  • Hyosyne Drops should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if Hyosyne Drops can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hyosyne Drops while you are pregnant. Hyosyne Drops are found in breast milk. If you are or will be breast-feeding while taking Hyosyne Drops, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Hyosyne Drops:


All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Bloated feeling; blurred vision; constipation; decreased sweating; dizziness; drowsiness; dry mouth; enlarged pupils; excitability; headache; nausea; nervousness; trouble sleeping; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; behavior changes; confusion; decreased sexual ability; diarrhea; difficulty focusing eyes; disorientation; exaggerated sense of well-being; fast or irregular heartbeat; hallucinations; loss of consciousness; loss of coordination; memory loss; mental or mood changes; severe or persistent trouble sleeping; speech changes; taste changes or loss; trouble urinating; unusual tiredness or weakness; vision changes; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Hyosyne side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include disorientation; excessive thirst or excitability; fever; hot, dry skin; seizures; severe dry mouth; severe or persistent blurred vision, dizziness, headache, nausea, or vomiting; trouble breathing or swallowing.


Proper storage of Hyosyne Drops:

Store Hyosyne Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Hyosyne Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Hyosyne Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Hyosyne Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Hyosyne Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Hyosyne resources


  • Hyosyne Side Effects (in more detail)
  • Hyosyne Use in Pregnancy & Breastfeeding
  • Hyosyne Drug Interactions
  • Hyosyne Support Group
  • 1 Review for Hyosyne - Add your own review/rating


Compare Hyosyne with other medications


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  • Endoscopy or Radiology Premedication
  • Irritable Bowel Syndrome
  • Urinary Incontinence

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