Thursday 26 April 2012

Tobramycin Drops



Pronunciation: toe-bra-MYE-sin
Generic Name: Tobramycin
Brand Name: Examples include AK-Tob and Tobrex


Tobramycin Drops are used for:

Treating eye infections.


Tobramycin Drops are an antibiotic. It works by killing or slowing the growth of certain types of bacteria.


Do NOT use Tobramycin Drops if:


  • you are allergic to any ingredient in Tobramycin Drops or to similar medicines

Contact your doctor or health care provider right away if any of these apply to you.



Before using Tobramycin Drops:


Some medical conditions may interact with Tobramycin Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Tobramycin Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Cephalosporins by injection (eg, ceftazidime) because they may decrease Tobramycin Drops's effectiveness

  • Cyclosporine, fludarabine, loop diuretics (eg, furosemide), methoxyflurane, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin), nitrosoureas (eg, streptozocin), polypeptide antibiotics (eg, polymyxin B), or vancomycin injection because they may increase the risk of Tobramycin Drops's side effects, including increased risk of kidney or hearing problems

  • Cephalosporins by injection (eg, ceftazidime), nondepolarizing muscle relaxants (eg, pancuronium), or succinylcholine because their side effects may be increased by Tobramycin Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tobramycin Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Tobramycin Drops:


Use Tobramycin Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Remove contact lenses before you use Tobramycin Drops.

  • Do not wear contact lenses while you are using Tobramycin Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.

  • To use Tobramycin Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.

  • To clear up your infection completely, take/use Tobramycin Drops for the full course of treatment. Keep taking/using it even if you feel better in a few days.

  • Tobramycin Drops works best if it is used at the same time each day.

  • Do not miss any doses. If you miss a dose of Tobramycin Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Tobramycin Drops.



Important safety information:


  • Tobramycin Drops may cause blurred vision. Use Tobramycin Drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.

  • If your symptoms do not get better within a few days or if they get worse, check with your doctor.

  • Be sure to use Tobramycin Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • Long-term or repeated use of Tobramycin Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

  • Tobramycin Drops should not be used in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tobramycin Drops while you are pregnant. It is not known if Tobramycin Drops are found in breast milk. Do not breast-feed while using Tobramycin Drops.


Possible side effects of Tobramycin Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Burning or stinging in the eye.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); eye or eyelid swelling, itching, or redness.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; eye pain; eye watering; swelling and itching of the eyelid.


Proper storage of Tobramycin Drops:

Store Tobramycin Drops at room temperature, between 46 and 80 degrees F (8 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tobramycin Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Tobramycin Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Tobramycin Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tobramycin Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tobramycin resources


  • Tobramycin Use in Pregnancy & Breastfeeding
  • Tobramycin Support Group
  • 3 Reviews for Tobramycin - Add your own review/rating


Compare Tobramycin with other medications


  • Conjunctivitis, Bacterial

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